产品详情
简单介绍:
Human MDH1 (Malate Dehydrogenase 1) Sandwich ELISA Kit Ready-To-Use (STJE0016931)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 27pg/mL |
Detection Limit: | 78.1-5000pg/mL |
Short Description: | This MDH1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | MDH1 |
Gene ID: | 4190 |
Uniprot ID: | MDHC_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | ISGylated. Acetylation at Lys-118 dramatically enhances enzymatic activity and promotes adipogenic differentiation. |
Function | Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH. Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation. Catalyzes the reduction of 2-oxoglutarate to 2-hydroxyglutarate, leading to elevated reactive oxygen species (ROS). |
Protein Name | Malate Dehydrogenase - Cytoplasmic Aromatic Alpha-Keto Acid Reductase Kar Cytosolic Malate Dehydrogenase |
Database Links | Reactome: R-HSA-70263 |
Cellular Localisation | Cytoplasm Cytosol |
Alternative ELISA Names | Malate Dehydrogenase - Cytoplasmic ELISA kit Aromatic Alpha-Keto Acid Reductase ELISA kit Kar ELISA kit Cytosolic Malate Dehydrogenase ELISA kit MDH1 ELISA kit MDHA ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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