产品详情

  • 产品名称：Anti-BCL2L2 antibody (1-193) (STJ22781)

  • 产品型号：STJ22781
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-BCL2L2 antibody (1-193) (STJ22781)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Bcl-W (1-193) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BCL2L2
Gene ID: 599
Uniprot ID: B2CL2_HUMAN
Immunogen Region: 1-193
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-193 of human Bcl-W (NP_004041.2).
Immunogen Sequence: MATPASAPDTRALVADFVGY KLRQKGYVCGAGPGEGPAAD PLHQAMRAAGDEFETRFRRT FSDLAAQLHVTPGSAQQRFT QVSDELFQGGPNWGRLVAFF VFGAALCAESVNKEMEPLVG QVQEWMVAYLETQLADWIHS SGGWAEFTALYGDGALEEAR RLREGNWASVRTVLTGAVAL GALVTVGAFFASK
Tissue Specificity Expressed (at protein level) in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands. Moderate levels found in thymus, ovary and small intestine. Not detected in salivary gland, muscle or liver. Also expressed in cell lines of myeloid, fibroblast and epithelial origin. Not detected in most lymphoid cell lines.
Function Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
Protein Name Bcl-2-Like Protein 2
Bcl2-L-2
Apoptosis Regulator Bcl-W
Cellular Localisation Mitochondrion Membrane
Peripheral Membrane Protein
Loosely Associated With The Mitochondrial Membrane In Healthy Cells
During Apoptosis
Tightly Bound To The Membrane
Alternative Antibody Names Anti-Bcl-2-Like Protein 2 antibody
Anti-Bcl2-L-2 antibody
Anti-Apoptosis Regulator Bcl-W antibody
Anti-BCL2L2 antibody
Anti-BCLW antibody
Anti-KIAA0271 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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