产品详情

  • 产品名称：Human LIPE (Lipase, Hormone Sensitive) Sandwich ELISA Kit (STJE0010355)

  • 产品型号：STJE0010355
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human LIPE (Lipase, Hormone Sensitive) Sandwich ELISA Kit (STJE0010355)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.067ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This LIPE Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: LIPE
Gene ID: 3991
Uniprot ID: LIPS_HUMAN
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity Testis.
Post Translational Modifications Phosphorylation by AMPK reduces its translocations towards the lipid droplets.
Function Lipase with broad substrate specificity, catalyzing the hydrolysis of triacylglycerols (TAGs), diacylglycerols (DAGs), monoacylglycerols (MAGs), cholesteryl esters and retinyl esters. Shows a preferential hydrolysis of DAGs over TAGs and MAGs and preferentially hydrolyzes the fatty acid (FA) esters at the sn-3 position of the glycerol backbone in DAGs. Preferentially hydrolyzes FA esters at the sn-1 and sn-2 positions of the glycerol backbone in TAGs. Catalyzes the hydrolysis of 2-arachidonoylglycerol, an endocannabinoid and of 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.
Protein Name Hormone-Sensitive Lipase
Hsl
Monoacylglycerol Lipase Lipe
Retinyl Ester Hydrolase
Reh
Database Links Reactome: R-HSA-163560
Cellular Localisation Cell Membrane
Membrane
Caveola
Cytoplasm
Cytosol
Lipid Droplet
Found In The High-Density Caveolae
Translocates To The Cytoplasm From The Caveolae Upon Insulin Stimulation
Phosphorylation By Ampk Reduces Its Translocations Towards The Lipid Droplets
Alternative ELISA Names Hormone-Sensitive Lipase ELISA kit
Hsl ELISA kit
Monoacylglycerol Lipase Lipe ELISA kit
Retinyl Ester Hydrolase ELISA kit
Reh ELISA kit
LIPE ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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