产品详情

  • 产品名称：Anti-CD123/IL3RA antibody [6H6] {PE/Cyanine5} (STJA0000706)

  • 产品型号：STJA0000706
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CD123/IL3RA antibody [6H6] {PE/Cyanine5} (STJA0000706)
详情介绍：
Host: Mouse
Applications: FC
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Interleukin-3 receptor subunit alpha is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: 6H6
Conjugation: PE/Cyanine5
Isotype: IgG1k
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: IL3RA
Gene ID: 3563
Uniprot ID: IL3RA_HUMAN
Post Translational Modifications Ubiquitinated by RNFT2 in response to IL3. Ubiquitination leads ligand-induced degradation by the proteasome.
Function Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program.
Protein Name Interleukin-3 Receptor Subunit Alpha
Il-3 Receptor Subunit Alpha
Il-3r Subunit Alpha
Il-3r-Alpha
Il-3ra
Cd Antigen Cd123
Database Links Reactome: R-HSA-512988
Reactome: R-HSA-5673001
Reactome: R-HSA-912526
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Interleukin-3 Receptor Subunit Alpha antibody
Anti-Il-3 Receptor Subunit Alpha antibody
Anti-Il-3r Subunit Alpha antibody
Anti-Il-3r-Alpha antibody
Anti-Il-3ra antibody
Anti-Cd Antigen Cd123 antibody
Anti-IL3RA antibody
Anti-IL3R antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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