产品详情

  • 产品名称：Anti-CD11b/ITGAM antibody [ICRF44] {PE/Cyanine5.5} (STJA0001877)

  • 产品型号：STJA0001877
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Anti-CD11b/ITGAM antibody [ICRF44] {PE/Cyanine5.5} (STJA0001877)
详情介绍：
Host: Mouse
Applications: FC
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Integrin alpha-M is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: ICRF44
Conjugation: PE/Cyanine5.5
Isotype: IgG1k
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: ITGAM
Gene ID: 3684
Uniprot ID: ITAM_HUMAN
Tissue Specificity Predominantly expressed in monocytes and granulocytes. Expressed in neutrophils (at protein level).
Function Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils. May regulate phagocytosis-induced apoptosis in extravasated neutrophils. May play a role in mast cell development. Required with TYROBP/DAP12 in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development.
Protein Name Integrin Alpha-M
Cd11 Antigen-Like Family Member B
Cr-3 Alpha Chain
Cell Surface Glycoprotein Mac-1 Subunit Alpha
Leukocyte Adhesion Receptor Mo1
Neutrophil Adherence Receptor
Cd Antigen Cd11b
Database Links Reactome: R-HSA-166016
Reactome: R-HSA-202733
Reactome: R-HSA-216083
Reactome: R-HSA-6785807
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Membrane Raft
Alternative Antibody Names Anti-Integrin Alpha-M antibody
Anti-Cd11 Antigen-Like Family Member B antibody
Anti-Cr-3 Alpha Chain antibody
Anti-Cell Surface Glycoprotein Mac-1 Subunit Alpha antibody
Anti-Leukocyte Adhesion Receptor Mo1 antibody
Anti-Neutrophil Adherence Receptor antibody
Anti-Cd Antigen Cd11b antibody
Anti-ITGAM antibody
Anti-CD11B antibody
Anti-CR3A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 
网站地图