产品详情

  • 产品名称：Anti-BAG5 antibody (Internal) (STJ71345)

  • 产品型号：STJ71345-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-BAG5 antibody (Internal) (STJ71345)
详情介绍：
Host: Goat
Applications: Pep-ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-BAG5 (Internal) is suitable for use in ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:16000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: BAG5
Gene ID: 9529
Uniprot ID: BAG5_HUMAN
Immunogen Region: Internal
Accession Number: NP_001015048.1; NP_001015049.1; NP_004864.1
Specificity: This antibody is expected to recognise reported isoforms a (NP_001015049.1) and b (NP_001015048.1, NP_004864.1).
Immunogen Sequence: DGNRTDKNYIR
Function Co-chaperone for HSP/HSP70 proteins. It functions as a nucleotide-exchange factor promoting the release of ADP from HSP70, thereby activating HSP70-mediated protein refolding. Has an essential role in maintaining proteostasis at junctional membrane complexes (JMC), where it may function as a scaffold between the HSPA8 chaperone and JMC proteins enabling correct, HSPA8-dependent JMC protein folding. Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN.
Protein Name Bag Family Molecular Chaperone Regulator 5
Bag-5
Bcl-2-Associated Athanogene 5
Database Links Reactome: R-HSA-3371453
Cellular Localisation In Cardiomyocytes
Localized At Specialized Membrane Contact Sites Between T-Tubules And The Sarcoplasmic Reticulum
Known As Junctional Membrane Complexes
Alternative Antibody Names Anti-Bag Family Molecular Chaperone Regulator 5 antibody
Anti-Bag-5 antibody
Anti-Bcl-2-Associated Athanogene 5 antibody
Anti-BAG5 antibody
Anti-KIAA0873 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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