产品详情
简单介绍:
Anti-CCL17 antibody (21-70 aa) (STJ194761)
详情介绍:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-C-C motif chemokine 17 (21-70 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA-Pep 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CCL17 |
Gene ID: | 6361 |
Uniprot ID: | CCL17_HUMAN |
Immunogen Region: | 21-70 aa |
Specificity: | This antibody detects endogenous levels of human CCL17 |
Immunogen: | Synthesized peptide derived from the human CCL17 at the amino acid range 21-70 |
Function | Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound. |
Protein Name | C-C Motif Chemokine 17 Cc Chemokine Tarc Small-Inducible Cytokine A17 Thymus And Activation-Regulated Chemokine |
Database Links | Reactome: R-HSA-380108 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-C-C Motif Chemokine 17 antibody Anti-Cc Chemokine Tarc antibody Anti-Small-Inducible Cytokine A17 antibody Anti-Thymus And Activation-Regulated Chemokine antibody Anti-CCL17 antibody Anti-SCYA17 antibody Anti-TARC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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