产品详情
简单介绍:
Anti-CCK antibody (21-115) (STJ11103880)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Cholecystokinin (21-115) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:100-1:500 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CCK |
Gene ID: | 885 |
Uniprot ID: | CCKN_HUMAN |
Immunogen Region: | 21-115 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-115 of human CCK (NP_000720.1). |
Immunogen Sequence: | QPVPPADPAGSGLQRAEEAP RRQLRVSQRTDGESRAHLGA LLARYIQQARKAPSGRMSIV KNLQNLDPSHRISDRDYMGW MDFGRRSAEEYEYPS |
Tissue Specificity | Detected in cerebrospinal fluid and urine (at protein level). |
Post Translational Modifications | The precursor is cleaved by proteases to produce a number of active cholecystokinins. Cholecystokinin-5: The precursor is cleaved by ACE, which removes the Gly-Arg-Arg peptide at the C-terminus, leading to mature hormone. |
Function | This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. |
Protein Name | Cholecystokinin Cck Cleaved Into - Cholecystokinin-58 Cck58 - Cholecystokinin-58 Desnonopeptide (1-49-Cck58 - Cholecystokinin-39 Cck39 - Cholecystokinin-33 Cck33 - Cholecystokinin-25 Cck25 - Cholecystokinin-18 Cck18 - Cholecystokinin-12 Cck12 - Cholecystokinin-8 Cck8 - Cholecystokinin-7 Cck7 - Cholecystokinin-5 Cck5 |
Database Links | Reactome: R-HSA-375276 Reactome: R-HSA-416476 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Cholecystokinin antibody Anti-Cck Cleaved Into - Cholecystokinin-58 antibody Anti-Cck58 - Cholecystokinin-58 Desnonopeptide antibody Anti-(1-49-Cck58 - Cholecystokinin-39 antibody Anti-Cck39 - Cholecystokinin-33 antibody Anti-Cck33 - Cholecystokinin-25 antibody Anti-Cck25 - Cholecystokinin-18 antibody Anti-Cck18 - Cholecystokinin-12 antibody Anti-Cck12 - Cholecystokinin-8 antibody Anti-Cck8 - Cholecystokinin-7 antibody Anti-Cck7 - Cholecystokinin-5 antibody Anti-Cck5 antibody Anti-CCK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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