产品详情
简单介绍:
Human IL5 (IL5) Sandwich ELISA Kit (STJE0000021)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.43 pg/mL |
Detection Limit: | 156-100 pg/ml |
Short Description: | This IL5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Conjugation: | Biotin |
Storage Instruction: | Unopened kits can be stored at 2-8°C for 1 year, and opened products must be used within 1 month. |
Assay Time: | 4 hours |
Detection: | Colorimetric |
Gene Symbol: | IL5 |
Gene ID: | 3567 |
Uniprot ID: | IL5_HUMAN |
Sample Type: | serum, plasma and cell culture supernates |
Tissue Specificity | |
Post Translational Modifications | |
Function | Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively. |
Protein Name | Interleukin-5 Il-5 B-Cell Differentiation Factor I Eosinophil Differentiation Factor T-Cell Replacing Factor Trf |
Database Links | Reactome: R-HSA-512988 Reactome: R-HSA-5673001 Reactome: R-HSA-912526 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Interleukin-5 ELISA kit Il-5 ELISA kit B-Cell Differentiation Factor I ELISA kit Eosinophil Differentiation Factor ELISA kit T-Cell Replacing Factor ELISA kit Trf ELISA kit IL5 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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