产品详情

  • 产品名称：Anti-CASP10 antibody (Internal) (STJ96459)

  • 产品型号：STJ96459
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CASP10 antibody (Internal) (STJ96459)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Caspase-10 (Internal) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CASP10
Gene ID: 843
Uniprot ID: CASPA_HUMAN
Immunogen Region: Internal
Specificity: Caspase-10 Polyclonal Antibody detects endogenous levels of Caspase-10 protein.
Immunogen: Synthesized peptide derived from the Internal region of human Caspase-10.
Post Translational Modifications Cleavage by granzyme B and autocatalytic activity generate the two active subunits.
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates effector caspases CASP3, CASP4, CASP6, CASP7, CASP8 and CASP9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform 7 can enhance NF-kappaB activity but promotes only slight apoptosis. Isoform C is proteolytically inactive.
Protein Name Caspase-10
Casp-10
Apoptotic Protease Mch-4
Fas-Associated Death Domain Protein Interleukin-1b-Converting Enzyme 2
Flice2
Ice-Like Apoptotic Protease 4 Cleaved Into - Caspase-10 Subunit P23/17 - Caspase-10 Subunit P12
Database Links Reactome: R-HSA-6803207
Reactome: R-HSA-75157
Reactome: R-HSA-75158
Reactome: R-HSA-933543
Alternative Antibody Names Anti-Caspase-10 antibody
Anti-Casp-10 antibody
Anti-Apoptotic Protease Mch-4 antibody
Anti-Fas-Associated Death Domain Protein Interleukin-1b-Converting Enzyme 2 antibody
Anti-Flice2 antibody
Anti-Ice-Like Apoptotic Protease 4 Cleaved Into - Caspase-10 Subunit P23/17 - Caspase-10 Subunit P12 antibody
Anti-CASP10 antibody
Anti-MCH4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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