产品详情
简单介绍:
Anti-C3AR1 antibody (161-337) (STJ28444)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-C3AR1 (161-337) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | C3AR1 |
Gene ID: | 719 |
Uniprot ID: | C3AR_HUMAN |
Immunogen Region: | 161-337 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 161-337 of human C3AR1 (NP_004045.1). |
Immunogen Sequence: | REIFTTDNHNRCGYKFGLSS SLDYPDFYGDPLENRSLENI VQPPGEMNDRLDPSSFQTND HPWTVPTVFQPQTFQRPSAD SLPRGSARLTSQNLYSNVFK PADVVSPKIPSGFPIEDHET SPLDNSDAFLSTHLKLFPSA SSNSFYESELPQGFQDYYNL GQFTDDDQVPTPLVAIT |
Tissue Specificity | Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues. |
Post Translational Modifications | Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin. O-glycosylated. |
Function | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. |
Protein Name | C3a Anaphylatoxin Chemotactic Receptor C3ar C3a-R |
Database Links | Reactome: R-HSA-375276 Reactome: R-HSA-418594 Reactome: R-HSA-6798695 Reactome: R-HSA-9660826 Reactome: R-HSA-977606 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-C3a Anaphylatoxin Chemotactic Receptor antibody Anti-C3ar antibody Anti-C3a-R antibody Anti-C3AR1 antibody Anti-AZ3B antibody Anti-C3R1 antibody Anti-HNFAG09 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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