产品详情
  • 产品名称:Anti-BLOC1S3 antibody (1-202) (STJ119421)

  • 产品型号:STJ119421
  • 产品厂商:ST john's laboratory
  • 产品文档:
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简单介绍:
Anti-BLOC1S3 antibody (1-202) (STJ119421)
详情介绍:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BLOC1S3 (1-202) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BLOC1S3
Gene ID: 388552
Uniprot ID: BL1S3_HUMAN
Immunogen Region: 1-202
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human BLOC1S3 (NP_997715.1).
Immunogen Sequence: MASQGRRRRPLRRPETVVPG EATETDSERSASSSEEEELY LGPSGPTRGRPTGLRVAGEA AETDSEPEPEPEPTAAPRDL PPLVVQRESAEEAWGTEEAP APAPARSLLQLRLAESQARL DHDVAAAVSGVYRRAGRDVA ALASRLAAAQAAGLAAAHSV RLARGDLCALAERLDIVAGC RLLPDIRGVPGTEPEKDPGP RA
Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.
Protein Name Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 3
Bloc-1 Subunit 3
Database Links Reactome: R-HSA-432722
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 3 antibody
Anti-Bloc-1 Subunit 3 antibody
Anti-BLOC1S3 antibody
Anti-BLOS3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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