产品详情
简单介绍:
Anti-BLOC1S3 antibody (1-202) (STJ119421)
详情介绍:
Host: | Rabbit |
Applications: | IHC/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-BLOC1S3 (1-202) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | IHC-P 1:50-1:200 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | BLOC1S3 |
Gene ID: | 388552 |
Uniprot ID: | BL1S3_HUMAN |
Immunogen Region: | 1-202 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human BLOC1S3 (NP_997715.1). |
Immunogen Sequence: | MASQGRRRRPLRRPETVVPG EATETDSERSASSSEEEELY LGPSGPTRGRPTGLRVAGEA AETDSEPEPEPEPTAAPRDL PPLVVQRESAEEAWGTEEAP APAPARSLLQLRLAESQARL DHDVAAAVSGVYRRAGRDVA ALASRLAAAQAAGLAAAHSV RLARGDLCALAERLDIVAGC RLLPDIRGVPGTEPEKDPGP RA |
Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. |
Protein Name | Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 3 Bloc-1 Subunit 3 |
Database Links | Reactome: R-HSA-432722 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 3 antibody Anti-Bloc-1 Subunit 3 antibody Anti-BLOC1S3 antibody Anti-BLOS3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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