产品详情
简单介绍:
Anti-BEST1 antibody (376-585) (STJ28302)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-BEST1 (376-585) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | BEST1 |
Gene ID: | 7439 |
Uniprot ID: | BEST1_HUMAN |
Immunogen Region: | 376-585 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 376-585 of human BEST1 (NP_004174.1). |
Immunogen Sequence: | QPNQEDEEDAHAGIIGRFLG LQSHDHHPPRANSRTKLLWP KRESLLHEGLPKNHKAAKQN VRGQEDNKAWKLKAVDAFKS APLYQRPGYYSAPQTPLSPT PMFFPLEPSAPSKLHSVTGI DTKDKSLKTVSSGAKKSFEL LSESDGALMEHPEVSQVRRK TVEFNLTDMPEIPENHLKEP LEQSPTNIHTTLKDHMDPYW ALENRDEAHS |
Tissue Specificity | Predominantly expressed in the basolateral membrane of the retinal pigment epithelium. |
Post Translational Modifications | Phosphorylated by PP2A. |
Function | Forms calcium-sensitive chloride channels. Highly permeable to bicarbonate. |
Protein Name | Bestrophin-1 Tu15b Vitelliform Macular Dystrophy Protein 2 |
Database Links | Reactome: R-HSA-2672351 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane |
Alternative Antibody Names | Anti-Bestrophin-1 antibody Anti-Tu15b antibody Anti-Vitelliform Macular Dystrophy Protein 2 antibody Anti-BEST1 antibody Anti-VMD2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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