产品详情
简单介绍:
Themis Positive Control peptide (STJ505196)
详情介绍:
Applications: | WB |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Themis Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: | WB: 1:500 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | THEMIS |
Gene ID: | 387357 |
Uniprot ID: | THMS1_HUMAN |
Post Translational Modifications | Phosphorylated on Tyr residues quickly after TCR stimulation. |
Function | Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk. |
Peptide Name | Protein Themis Thymocyte-Expressed Molecule Involved In Selection |
Cellular Localisation | Cytoplasm Nucleus |
Alternative Peptide Names | Protein Themis protein Thymocyte-Expressed Molecule Involved In Selection protein THEMIS protein C6orf190 protein C6orf207 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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