产品详情
简单介绍:
Mouse TNFRSF18/CD357 protein (Recombinant) (C-Fc & His) (STJP002076)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Mouse TNFRSF18/CD357-C-Fc & His protein was developed from hek293 cells and has a target region of C-Fc & His. For use in research applications. |
Formulation: | Lyophilized from a 0.2 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | Tnfrsf18 |
Gene ID: | 21936 |
Uniprot ID: | TNR18_MOUSE |
Immunogen Region: | Ser22-His153 |
Immunogen: | Recombinant Mouse TNFRSF18/CD357 Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Ser22-His153) of mouse GITR (Accession #O35714) fused with an Fc, 6xHis tag at the C-terminus. |
Function | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 18 Glucocorticoid-Induced Tnfr-Related Protein Cd Antigen Cd357 |
Database Links | Reactome: R-MMU-5669034 |
Cellular Localisation | Isoform A: Cell Membrane Single-Pass Type I Membrane Protein Isoform B: Cell Membrane Isoform C: Cell Membrane Isoform D: Secreted |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 18 protein Glucocorticoid-Induced Tnfr-Related Protein protein Cd Antigen Cd357 protein Tnfrsf18 protein Gitr protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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