产品详情

  • 产品名称：Anti-ARIH2 antibody (STJA0004349)

  • 产品型号：STJA0004349
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ARIH2 antibody (STJA0004349)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-E3 Ubiquitin-Protein Ligase Arih2 is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification: Affinity purification
Concentration: 0.6 mg/mL
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: ARIH2
Gene ID: 10425
Uniprot ID: ARI2_HUMAN
Immunogen: Synthetic peptide of human ARIH2
Tissue Specificity Widely expressed with higher expression in granulocytes.
Post Translational Modifications Ubiquitinated. Ubiquitination promotes proteasomal degradation.
Function E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3. Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-5-RING ubiquitin ligase complex (ECS complex, also named CRL5 complex) and initiating ubiquitination of ECS substrates: associates with ECS complex and specifically mediates addition of the first ubiquitin on ECS targets. The initial ubiquitin is then elongated. E3 ubiquitin-protein ligase activity is activated upon binding to neddylated form of the ECS complex. Mediates 'Lys-6', 'Lys-48'- and 'Lys-63'-linked polyubiquitination. May play a role in myelopoiesis.
Protein Name E3 Ubiquitin-Protein Ligase Arih2
Ari-2
Protein Ariadne-2 Homolog
Ring-Type E3 Ubiquitin Transferase Arih2
Triad1 Protein
Database Links Reactome: R-HSA-983168
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-E3 Ubiquitin-Protein Ligase Arih2 antibody
Anti-Ari-2 antibody
Anti-Protein Ariadne-2 Homolog antibody
Anti-Ring-Type E3 Ubiquitin Transferase Arih2 antibody
Anti-Triad1 Protein antibody
Anti-ARIH2 antibody
Anti-ARI2 antibody
Anti-TRIAD1 antibody
Anti-HT005 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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