产品详情

  • 产品名称：Anti-alpha-2-macroglobulin antibody (Internal) (STJ73369)

  • 产品型号：STJ73369-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-alpha-2-macroglobulin antibody (Internal) (STJ73369)
详情介绍：
Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-alpha-2-macroglobulin (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.5-2µg/ml
IHC-5µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: A2M
Gene ID: 2
Uniprot ID: A2MG_HUMAN
Immunogen Region: Internal
Accession Number: NP_000005.2
Immunogen Sequence: TSLTVRVNYKDRSP
Function Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
Protein Name Alpha-2-Macroglobulin
Alpha-2-M
C3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 5
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-140837
Reactome: R-HSA-1474228
Reactome: R-HSA-8963896
Cellular Localisation Secreted
Alternative Antibody Names Anti-Alpha-2-Macroglobulin antibody
Anti-Alpha-2-M antibody
Anti-C3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 5 antibody
Anti-A2M antibody
Anti-CPAMD5 antibody
Anti-FWP007 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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