产品详情

  • 产品名称：Human CES1 (Carboxylesterase 1) Sandwich ELISA Kit (STJE0007882)

  • 产品型号：STJE0007882
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human CES1 (Carboxylesterase 1) Sandwich ELISA Kit (STJE0007882)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.072ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This CES1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: CES1
Gene ID: 1066
Uniprot ID: EST1_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed predominantly in liver with lower levels in heart and lung. Expressed in macrophages.
Post Translational Modifications Contains sialic acid. Cleavage of the signal sequence can occur at 2 positions, either between Trp-17 and Gly-18 or between Gly-18 and His-19.
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins. Hydrolyzes cellular cholesteryl esters to free cholesterols and promotes reverse cholesterol transport (RCT) by facilitating both the initial and final steps in the process. First of all, allows free cholesterol efflux from macrophages to extracellular cholesterol acceptors and secondly, releases free cholesterol from lipoprotein-delivered cholesteryl esters in the liver for bile acid synthesis or direct secretion into the bile.
Protein Name Liver Carboxylesterase 1
Acyl-Coenzyme A -Cholesterol Acyltransferase
Acat
Brain Carboxylesterase Hbr1
Carboxylesterase 1
Ce-1
Hce-1
Cholesteryl Ester Hydrolase
Ceh
Cocaine Carboxylesterase
Egasyn
Hmse
Methylumbelliferyl-Acetate Deacetylase 1
Monocyte/Macrophage Serine Esterase
Retinyl Ester Hydrolase
Reh
Serine Esterase 1
Triacylglycerol Hydrolase
Tgh
Database Links Reactome: R-HSA-2022377
Reactome: R-HSA-211945
Reactome: R-HSA-5578768
Reactome: R-HSA-9749641
Cellular Localisation Endoplasmic Reticulum Lumen
Cytoplasm
Lipid Droplet
Moves From Cytoplasm To Lipid Droplets Upon Lipid Loading
Associates With Lipid Droplets Independently Of Triglycerides (Tg) Content Of The Droplets And Hydrolyzes Cholesteryl Esters More Efficiently From Mixed Droplets
Alternative ELISA Names Liver Carboxylesterase 1 ELISA kit
Acyl-Coenzyme A -Cholesterol Acyltransferase ELISA kit
Acat ELISA kit
Brain Carboxylesterase Hbr1 ELISA kit
Carboxylesterase 1 ELISA kit
Ce-1 ELISA kit
Hce-1 ELISA kit
Cholesteryl Ester Hydrolase ELISA kit
Ceh ELISA kit
Cocaine Carboxylesterase ELISA kit
Egasyn ELISA kit
Hmse ELISA kit
Methylumbelliferyl-Acetate Deacetylase 1 ELISA kit
Monocyte/Macrophage Serine Esterase ELISA kit
Retinyl Ester Hydrolase ELISA kit
Reh ELISA kit
Serine Esterase 1 ELISA kit
Triacylglycerol Hydrolase ELISA kit
Tgh ELISA kit
CES1 ELISA kit
CES2 ELISA kit
SES1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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