产品详情
简单介绍：
Anti-BAIAP2 antibody (STJA0007475)
详情介绍：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Brain-specific angiogenesis inhibitor 1-associated protein 2 is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BAIAP2 |
| Gene ID: | 10458 |
| Uniprot ID: | BAIP2_HUMAN |
| Specificity: | This antibody detects endogenous levels of IRSp53 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human IRSp53 |
| Post Translational Modifications | Phosphorylated on tyrosine residues by INSR in response to insulin treatment. |
| Function | Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodsia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions. |
| Protein Name | Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 Bai-Associated Protein 2 Bai1-Associated Protein 2 Protein Bap2 Fas Ligand-Associated Factor 3 Flaf3 Insulin Receptor Substrate P53/P58 Irs-58 Irsp53/58 Insulin Receptor Substrate Protein Of 53 Kda Irsp53 Insulin Receptor Substrate P53 |
| Database Links | Reactome: R-HSA-2029482 Reactome: R-HSA-4420097 Reactome: R-HSA-5663213 Reactome: R-HSA-9013148 Reactome: R-HSA-9013149 Reactome: R-HSA-9013423 Reactome: R-HSA-9664422 |
| Cellular Localisation | Cytoplasm Membrane Peripheral Membrane Protein Cell Projection Filopodium Ruffle Cytoskeleton Detected Throughout The Cytoplasm In The Absence Of Specific Binding Partners Detected In Filopodia And Close To Membrane Ruffles Recruited To Actin Pedestals That Are Formed Upon Infection By Bacteria At Bacterial Attachment Sites |
| Alternative Antibody Names | Anti-Brain-Specific Angiogenesis Inhibitor 1-Associated Protein 2 antibody Anti-Bai-Associated Protein 2 antibody Anti-Bai1-Associated Protein 2 antibody Anti-Protein Bap2 antibody Anti-Fas Ligand-Associated Factor 3 antibody Anti-Flaf3 antibody Anti-Insulin Receptor Substrate P53/P58 antibody Anti-Irs-58 antibody Anti-Irsp53/58 antibody Anti-Insulin Receptor Substrate Protein Of 53 Kda antibody Anti-Irsp53 antibody Anti-Insulin Receptor Substrate P53 antibody Anti-BAIAP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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