产品详情
简单介绍:
Anti-BACH1 antibody (1-736) (STJ11100910)
详情介绍:
Host: | Rabbit |
Applications: | WB/IP |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-BACH1 (1-736) is suitable for use in Western Blot and Immunoprecipitation research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:1000-1:5000 IP 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | BACH1 |
Gene ID: | 571 |
Uniprot ID: | BACH1_HUMAN |
Immunogen Region: | 1-736 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-736 of human BACH1 (NP_996749.1). |
Immunogen Sequence: | MSLSENSVFAYESSVHSTNV LLSLNDQRKKDVLCDVTIFV EGQRFRAHRSVLAACSSYFH SRIVGQADGELNITLPEEVT VKGFEPLIQFAYTAKLILSK ENVDEVCKCVEFLSVHNIEE SCFQFLKFKFLDSTADQQEC PRKKCFSSHCQKTDLKLSLL DQRDLETDEVEEFLENKNVQ TPQCKLRRYQGNAKASPPLQ DSASQTYESMCLEKDAALAL PSLCPKYRKFQKAFGTDRV |
Post Translational Modifications | Ubiquitinated by the SCF(FBXL17) complex, leading to its degradation by the proteasome. |
Function | Transcriptional regulator that acts as repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites. Plays important roles in coordinating transcription activation and repression by MAFK. Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway. |
Protein Name | Transcription Regulator Protein Bach1 Btb And Cnc Homolog 1 Ha2303 |
Database Links | Reactome: R-HSA-9707587 Reactome: R-HSA-9707616 Reactome: R-HSA-9708530 Reactome: R-HSA-9818027 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Transcription Regulator Protein Bach1 antibody Anti-Btb And Cnc Homolog 1 antibody Anti-Ha2303 antibody Anti-BACH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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