产品详情

  • 产品名称：VPS36 Positive Control for STJ503505 peptide (STJ505629)

  • 产品型号：STJ505629-5
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
VPS36 Positive Control for STJ503505 peptide (STJ505629)
详情介绍：
Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: VPS36 Positive Control for STJ503505 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:2, 500-1:5, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: VPS36
Gene ID: 51028
Uniprot ID: VPS36_HUMAN
Specificity: This is positive control is recommended for use in combination with VPS36 antibody STJ503505.
Immunogen: Purfied protein.
Function Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.
Peptide Name Vacuolar Protein-Sorting-Associated Protein 36
Ell-Associated Protein Of 45 Kda
Escrt-Ii Complex Subunit Vps36
Database Links Reactome: R-HSA-917729
Reactome: R-HSA-9610379
Cellular Localisation Cytoplasm
Endosome
Late Endosome
Membrane
Nucleus
Colocalizes With Ubiquitinated Proteins On Late Endosomes
Recruited To The Endosome Membrane To Participate In Vesicle Formation
Alternative Peptide Names Vacuolar Protein-Sorting-Associated Protein 36 protein
Ell-Associated Protein Of 45 Kda protein
Escrt-Ii Complex Subunit Vps36 protein
VPS36 protein
C13orf9 protein
EAP45 protein
CGI-145 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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