产品详情

  • 产品名称：Human DCD (Dermcidin) Sandwich ELISA Kit Ready-To-Use (STJE0014746)

  • 产品型号：STJE0014746
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human DCD (Dermcidin) Sandwich ELISA Kit Ready-To-Use (STJE0014746)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.31ng/mL
Detection Limit: 0.781-50ng/mL
Short Description: This DCD Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: DCD
Gene ID: 117159
Uniprot ID: DCD_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Detected in urine (at protein level). Constitutively expressed in eccrine sweat gland cells (at protein level). Secreted into the sweat at a concentration of 1-10 micrograms/ml.
Post Translational Modifications
Function DCD-1: Found in sweat, has an antimicrobial activity during early bacterial colonization. The secreted peptide assembles into homohexameric complexes that can associate with and also insert into pathogen membranes. Once inserted in bacteria membranes forms anion channels probably altering the transmembrane potential essential for bacterial survival. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C-terminal side of Arg and, to a lesser extent, Lys residues. Survival-promoting peptide: Promotes survival of neurons and displays phosphatase activity. It may bind IgG.
Protein Name Dermcidin
Preproteolysin Cleaved Into - Survival-Promoting Peptide - Dcd-1
Database Links Reactome: R-HSA-6803157
Cellular Localisation Secreted
Survival-Promoting Peptide: Secreted
Dcd-1: Secreted
Membrane
Peripheral Membrane Protein
Single-Pass Membrane Protein
The Secreted Peptide Assembles Into Homohexameric Complexes That Can Probably Associate With Pathogen Membranes And Also Insert Into These Membranes Where They Behave As Channels
Alternative ELISA Names Dermcidin ELISA kit
Preproteolysin Cleaved Into - Survival-Promoting Peptide - Dcd-1 ELISA kit
DCD ELISA kit
AIDD ELISA kit
DSEP ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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