产品详情

  • 产品名称：Anti-ATP6AP2 antibody (171-220 aa) (STJ95413)

  • 产品型号：STJ95413
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ATP6AP2 antibody (171-220 aa) (STJ95413)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Renin receptor-transporting lysosomal accessory protein 2-transporting lysosomal-interacting protein 2 (171-220 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research appli
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ATP6AP2
Gene ID: 10159
Uniprot ID: RENR_HUMAN
Immunogen Region: 171-220 aa
Specificity: Renin Receptor Polyclonal Antibody detects endogenous levels of Renin Receptor protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Caper at the amino acid range 171-220
Post Translational Modifications Phosphorylated. Proteolytically cleaved by a furin-like convertase in the trans-Golgi network to generate N- and C-terminal fragments.
Function Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the lysosomal proton-transporting V-type ATPase (V-ATPase) and the acidification of the endo-lysosomal system. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, may also play a role in the renin-angiotensin system (RAS). Through its function in V-type ATPase (v-ATPase) assembly and acidification of the lysosome it regulates protein degradation and may control different signaling pathways important for proper brain development, synapse morphology and synaptic transmission.
Protein Name Renin Receptor
Atpase H(+-Transporting Lysosomal Accessory Protein 2
Atpase H(+-Transporting Lysosomal-Interacting Protein 2
Er-Localized Type I Transmembrane Adapter
Embryonic Liver Differentiation Factor 10
N14f
Renin/Prorenin Receptor
Vacuolar Atp Synthase Membrane Sector-Associated Protein M8-9
Atp6m8-9
V-Atpase M8.9 Subunit Cleaved Into - Renin Receptor N-Terminal Fragment - Renin Receptor C-Terminal Fragment
Database Links Reactome: R-HSA-2022377
Reactome: R-HSA-6798695
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Lysosome Membrane
Cytoplasmic Vesicle
Autophagosome Membrane
Cell Projection
Dendritic Spine Membrane
Axon
Endosome Membrane
Clathrin-Coated Vesicle Membrane
Secretory Vesicle
Synaptic Vesicle Membrane
Alternative Antibody Names Anti-Renin Receptor antibody
Anti-Atpase H(+-Transporting Lysosomal Accessory Protein 2 antibody
Anti-Atpase H(+-Transporting Lysosomal-Interacting Protein 2 antibody
Anti-Er-Localized Type I Transmembrane Adapter antibody
Anti-Embryonic Liver Differentiation Factor 10 antibody
Anti-N14f antibody
Anti-Renin/Prorenin Receptor antibody
Anti-Vacuolar Atp Synthase Membrane Sector-Associated Protein M8-9 antibody
Anti-Atp6m8-9 antibody
Anti-V-Atpase M8.9 Subunit Cleaved Into - Renin Receptor N-Terminal Fragment - Renin Receptor C-Terminal Fragment antibody
Anti-ATP6AP2 antibody
Anti-ATP6IP2 antibody
Anti-CAPER antibody
Anti-ELDF10 antibody
Anti-HT028 antibody
Anti-MSTP009 antibody
Anti-PSEC0072 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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