产品详情

  • 产品名称：Human CYP11A1 (Cytochrome P450 11A1) Sandwich ELISA Kit Ready-To-Use (STJE0014676)

  • 产品型号：STJE0014676
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human CYP11A1 (Cytochrome P450 11A1) Sandwich ELISA Kit Ready-To-Use (STJE0014676)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.133ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This CYP11A1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: CYP11A1
Gene ID: 1583
Uniprot ID: CP11A_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
Protein Name Cholesterol Side-Chain Cleavage Enzyme - Mitochondrial
Cypxia1
Cholesterol Desmolase
Cytochrome P450 11a1
Cytochrome P450(Scc
Database Links Reactome: R-HSA-196108
Reactome: R-HSA-211976
Reactome: R-HSA-5579026
Cellular Localisation Mitochondrion Inner Membrane
Peripheral Membrane Protein
Localizes To The Matrix Side Of The Mitochondrion Inner Membrane
Alternative ELISA Names Cholesterol Side-Chain Cleavage Enzyme - Mitochondrial ELISA kit
Cypxia1 ELISA kit
Cholesterol Desmolase ELISA kit
Cytochrome P450 11a1 ELISA kit
Cytochrome P450(Scc ELISA kit
CYP11A1 ELISA kit
CYP11A ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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