产品详情

  • 产品名称：Human CYBb (Cytochrome b-245 Beta Polypeptide) Sandwich ELISA Kit Ready-To-Use (STJE0014668)

  • 产品型号：STJE0014668
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human CYBb (Cytochrome b-245 Beta Polypeptide) Sandwich ELISA Kit Ready-To-Use (STJE0014668)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This CYBb Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: CYBB
Gene ID: 1536
Uniprot ID: CY24B_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Detected in neutrophils (at protein level).
Post Translational Modifications Glycosylated. Phosphorylated on Ser and Thr residues. Undergoes 'Lys-48'-linked polyubiquitination, likely by RNF145, triggering endoplasmic reticulum-associated degradation.
Function Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
Protein Name Cytochrome B-245 Heavy Chain
Cgd91-Phox
Cytochrome B(558 Subunit Beta
Cytochrome B558 Subunit Beta
Heme-Binding Membrane Glycoprotein Gp91phox
Nadph Oxidase 2
Neutrophil Cytochrome B 91 Kda Polypeptide
Superoxide-Generating Nadph Oxidase Heavy Chain Subunit
Gp91-1
Gp91-Phox
P22 Phagocyte B-Cytochrome
Database Links Reactome: R-HSA-1222556
Reactome: R-HSA-1236973
Reactome: R-HSA-3299685
Reactome: R-HSA-4420097
Reactome: R-HSA-5668599
Reactome: R-HSA-6798695
Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013423
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
As Unassembled Monomer May Localize To The Endoplasmic Reticulum
Alternative ELISA Names Cytochrome B-245 Heavy Chain ELISA kit
Cgd91-Phox ELISA kit
Cytochrome B(558 Subunit Beta ELISA kit
Cytochrome B558 Subunit Beta ELISA kit
Heme-Binding Membrane Glycoprotein Gp91phox ELISA kit
Nadph Oxidase 2 ELISA kit
Neutrophil Cytochrome B 91 Kda Polypeptide ELISA kit
Superoxide-Generating Nadph Oxidase Heavy Chain Subunit ELISA kit
Gp91-1 ELISA kit
Gp91-Phox ELISA kit
P22 Phagocyte B-Cytochrome ELISA kit
CYBB ELISA kit
NOX2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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