产品详情
简单介绍:
Anti-ANKRD13A antibody (1-240) (STJ113670)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ANKRD13A (1-240) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ANKRD13A |
Gene ID: | 88455 |
Uniprot ID: | AN13A_HUMAN |
Immunogen Region: | 1-240 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ANKRD13A (NP_149112.1). |
Immunogen Sequence: | MSSACDAGDHYPLHLLVWKN DYRQLEKELQGQNVEAVDPR GRTLLHLAVSLGHLESARVL LRHKADVTKENRQGWTVLHE AVSTGDPEMVYTVLQHRDYH NTSMALEGVPELLQKILEAP DFYVQMKWEFTSWVPLVSRI CPNDVCRIWKSGAKLRVDIT LLGFENMSWIRGRRSFIFKG EDNWAELMEVNHDDKVVTTE RFDLSQEMERLTLDLMKPKS REVERRLTSPVINTSLDTK |
Post Translational Modifications | Monoubiquitinated, inhibits interaction with ubiquitinated EGFR. |
Function | Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. |
Protein Name | Ankyrin Repeat Domain-Containing Protein 13a Protein Ke03 |
Cellular Localisation | Cell Membrane Late Endosome Interaction With Egfr May Enhance Association With The Cell Membrane |
Alternative Antibody Names | Anti-Ankyrin Repeat Domain-Containing Protein 13a antibody Anti-Protein Ke03 antibody Anti-ANKRD13A antibody Anti-ANKRD13 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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