产品详情

  • 产品名称：STIM2 Positive Control for STJ503143 peptide (STJ505176)

  • 产品型号：STJ505176-5
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
STIM2 Positive Control for STJ503143 peptide (STJ505176)
详情介绍：
Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: STIM2 Positive Control for STJ503143 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: STIM2
Gene ID: 57620
Uniprot ID: STIM2_HUMAN
Specificity: This is positive control is recommended for use in combination with STIM2 antibody STJ503143.
Tissue Specificity Expressed in all tissues and tumor cell lines examined.
Post Translational Modifications Glycosylated. Phosphorylated predominantly on Ser residues.
Function Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx.
Peptide Name Stromal Interaction Molecule 2
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Dynamically Translocates From A Uniform Endoplasmic Reticulum Distribution To Punctual Endoplasmic Reticulum-Plasma Membrane Junctions In Response To Decrease In Endoplasmic Reticulum Ca(2+) Concentration
Alternative Peptide Names Stromal Interaction Molecule 2 protein
STIM2 protein
KIAA1482 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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