产品详情

  • 产品名称：Human COL11A1 (Collagen alpha-1 (XI) chain) CLIA Kit (STJC0000410)

  • 产品型号：STJC0000410
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human COL11A1 (Collagen alpha-1 (XI) chain) CLIA Kit (STJC0000410)
详情介绍：
Applications: CLIA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity: 9.38pg/mL
Detection Limit: 15.63~1000pg/mL
Short Description: This human COL11A1 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Storage Instruction: If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time: 3.5h
Detection: Chemiluminescence
Gene Symbol: COL11A1
Gene ID: 1301
Uniprot ID: COBA1_HUMAN
Specificity: This kit recognizes Human COL11 Alpha 1 in samples. No significant cross-reactivity or interference between Human COL11 Alpha 1 and analogues was observed.
Sample Type: Serum, plasma and other biological fluids
Tissue Specificity Cartilage, placenta and some tumor or virally transformed cell lines. Isoforms using exon IIA or IIB are found in the cartilage while isoforms using only exon IIB are found in the tendon.
Post Translational Modifications Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. N-glycosylated.
Function May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
Protein Name Collagen Alpha-1(Xi Chain
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1650814
Reactome: R-HSA-2022090
Reactome: R-HSA-3000171
Reactome: R-HSA-8874081
Reactome: R-HSA-8948216
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative CLIA Names Collagen Alpha-1(Xi Chain CLIA kit
COL11A1 CLIA kit
COLL6 CLIA kit
Specificity This kit recognizes Human COL11α1 in samples. No significant cross-reactivity or interference between Human COL11α1 and analogues was observed.
Reproducibility Both intra-CV and inter-CV are

Information sourced from Uniprot.org


Item Specifications Storage
Micro CLIA Plate (Dismountable) 96T: 8 wells ×12 strips strips -20℃, 6 months
Reference Standard 96T: 2 vials 48T: 1 vial -20℃, 6 months
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL 60 μL -20℃, 6 months
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL 60 μL -20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL 2-8°C, 6 months
HRP Conjugate Diluent 1 vial, 14 mL 2-8°C, 6 months
Concentrated Wash Buffer (25×) 1 vial, 30 mL 2-8°C, 6 months
Substrate Reagent A 1 vial, 5 mL 2-8℃ (Protect from light)
Substrate Reagent B 1 vial, 5 mL 2-8℃ (Protect from light)
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 97-110 102
EDTA plasma(n=8) 89-103 96
Cell culture media(n=8) 90-103 95

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision
Sample 1.00 2.00 3.00 1.00 2.00 3.00
n 20.00 20.00 20.00 20.00 20.00 20.00
Mean (pg/mL) 51.42 150.62 479.24 54.81 162.35 526.35
Standard deviation 6.07 15.23 48.59 5.95 12.99 53.90
CV (%) 11.80 10.11 10.14 10.86 8.00 10.24
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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