产品详情
简单介绍:
Human CLIC1 (Chloride Intracellular Channel Protein 1) Sandwich ELISA Kit (STJE0007991)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.123ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This CLIC1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | CLIC1 |
Gene ID: | 1192 |
Uniprot ID: | CLIC1_HUMAN |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expression is prominent in heart, placenta, liver, kidney and pancreas. |
Post Translational Modifications | Hydrogen peroxide treatment causes a conformation change, leading to dimerization and formation of an intramolecular disulfide bond between Cys-24 and Cys-59. |
Function | Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle. |
Protein Name | Chloride Intracellular Channel Protein 1 Chloride Channel Abp Nuclear Chloride Ion Channel 27 Ncc27 Regulatory Nuclear Chloride Ion Channel Protein Hrncc |
Database Links | |
Cellular Localisation | Nucleus Nucleus Membrane Single-Pass Membrane Protein Cytoplasm Cell Membrane Endoplasmic Reticulum Mostly In The Nucleus Including In The Nuclear Membrane Small Amount In The Cytoplasm And The Plasma Membrane Exists Both As Soluble Cytoplasmic Protein And As Membrane Protein With Probably A Single Transmembrane Domain Might Not Be Present In The Nucleus Of Cardiac Cells |
Alternative ELISA Names | Chloride Intracellular Channel Protein 1 ELISA kit Chloride Channel Abp ELISA kit Nuclear Chloride Ion Channel 27 ELISA kit Ncc27 ELISA kit Regulatory Nuclear Chloride Ion Channel Protein ELISA kit Hrncc ELISA kit CLIC1 ELISA kit G6 ELISA kit NCC27 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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