产品详情

  • 产品名称：Human CLCA1 (Chloride Channel Accessory 1) Sandwich ELISA Kit Ready-To-Use (STJE0014345)

  • 产品型号：STJE0014345
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human CLCA1 (Chloride Channel Accessory 1) Sandwich ELISA Kit Ready-To-Use (STJE0014345)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.056ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This CLCA1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: CLCA1
Gene ID: 1179
Uniprot ID: CLCA1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Highly expressed in small intestine and colon namely in intestinal basal crypt epithelia and goblet cells, and appendix. Weakly expressed in uterus, testis and kidney. Expressed in the airways epithelium of both asthmatic and healthy patients. Expressed in the bronchial epithelium, especially in mucus-producing goblet cells. Expressed in normal turbinate mucosa and nasal polyp. Expressed in.
Post Translational Modifications Glycosylated. The 125-kDa product is autoproteolytically processed by the metalloprotease domain and yields to two cell-surface-associated subunits, a 90-kDa protein and a group of 37- to 41-kDa proteins. The cleavage is necessary for calcium-activated chloride channel (CaCC) activation activity.
Function May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC.
Protein Name Calcium-Activated Chloride Channel Regulator 1
Calcium-Activated Chloride Channel Family Member 1
Hclca1
Calcium-Activated Chloride Channel Protein 1
Cacc-1
Hcacc-1
Database Links Reactome: R-HSA-2672351
Cellular Localisation Secreted
Extracellular Space
Cell Membrane
Peripheral Membrane Protein
Extracellular Side
Protein That Remains Attached To The Plasma Membrane Appeared To Be Predominantly Localized To Microvilli
Alternative ELISA Names Calcium-Activated Chloride Channel Regulator 1 ELISA kit
Calcium-Activated Chloride Channel Family Member 1 ELISA kit
Hclca1 ELISA kit
Calcium-Activated Chloride Channel Protein 1 ELISA kit
Cacc-1 ELISA kit
Hcacc-1 ELISA kit
CLCA1 ELISA kit
CACC1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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