产品详情

  • 产品名称：Anti-AREL1 antibody (354-404 aa) (STJ198007)

  • 产品型号：STJ198007
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-AREL1 antibody (354-404 aa) (STJ198007)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Apoptosis-resistant E3 ubiquitin protein ligase 1 (354-404 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AREL1
Gene ID: 9870
Uniprot ID: AREL1_HUMAN
Immunogen Region: 354-404 aa
Specificity: This antibody detects endogenous levels of human K0317
Immunogen: Synthesized peptide derived from the human K0317 at the amino acid range 354-404
Function E3 ubiquitin-protein ligase that catalyzes 'Lys-11'- or 'Lys-33'-linked polyubiquitin chains, with some preference for 'Lys-33' linkages. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates SEPTIN4, DIABLO/SMAC and HTRA2 in vitro. Modulates pulmonary inflammation by targeting SOCS2 for ubiquitination and subsequent degradation by the proteasome.
Protein Name Apoptosis-Resistant E3 Ubiquitin Protein Ligase 1
Apoptosis-Resistant Hect-Type E3 Ubiquitin Transferase 1
Database Links Reactome: R-HSA-983168
Alternative Antibody Names Anti-Apoptosis-Resistant E3 Ubiquitin Protein Ligase 1 antibody
Anti-Apoptosis-Resistant Hect-Type E3 Ubiquitin Transferase 1 antibody
Anti-AREL1 antibody
Anti-KIAA0317 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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