产品详情
简单介绍:
Anti-ARAF antibody (371-606) (STJ118774)
详情介绍:
Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ARAF (371-606) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ARAF |
Gene ID: | 369 |
Uniprot ID: | ARAF_HUMAN |
Immunogen Region: | 371-606 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 371-606 of human ARAF (NP_001645.1). |
Immunogen Sequence: | GFMTRPGFAIITQWCEGSSL YHHLHVADTRFDMVQLIDVA RQTAQGMDYLHAKNIIHRDL KSNNIFLHEGLTVKIGDFGL ATVKTRWSGAQPLEQPSGSV LWMAAEVIRMQDPNPYSFQS DVYAYGVVLYELMTGSLPYS HIGCRDQIIFMVGRGYLSPD LSKISSNCPKAMRRLLSDCL KFQREERPLFPQILATIELL QRSLPKIERSASEPSLHRTQ ADELPACLLSAARLVP |
Tissue Specificity | Predominantly in urogenital tissues. |
Function | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Phosphorylates PFKFB2. Isoform 2: Serves as a positive regulator of myogenic differentiation by inducing cell cycle arrest, the expression of myogenin and other muscle-specific proteins, and myotube formation. |
Protein Name | Serine/Threonine-Protein Kinase A-Raf Proto-Oncogene A-Raf Proto-Oncogene A-Raf-1 Proto-Oncogene Pks |
Database Links | Reactome: R-HSA-5673000 Reactome: R-HSA-5674135 Reactome: R-HSA-5675221 Reactome: R-HSA-6802946 Reactome: R-HSA-6802948 Reactome: R-HSA-6802952 Reactome: R-HSA-6802955 Reactome: R-HSA-9649948 Reactome: R-HSA-9656223 Reactome: R-HSA-9726840 Reactome: R-HSA-9726842 |
Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase A-Raf antibody Anti-Proto-Oncogene A-Raf antibody Anti-Proto-Oncogene A-Raf-1 antibody Anti-Proto-Oncogene Pks antibody Anti-ARAF antibody Anti-ARAF1 antibody Anti-PKS antibody Anti-PKS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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