产品详情
简单介绍:
PTBP2 Blocking Peptide for STJ506038 peptide (STJ505790)
详情介绍:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | PTBP2 Blocking Peptide for STJ506038 is synthetically produced from the 150-200 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | PTBP2 |
Gene ID: | 58155 |
Uniprot ID: | PTBP2_HUMAN |
Immunogen Region: | 150-200 |
Specificity: | This blocking peptide is recommended for use in combination with PTBP2 antibody, STJ506038 |
Immunogen: | Synthetic peptide taken within amino acid region 150-200 on human Polypyrimidine tract-binding protein 2/PTBP2. |
Tissue Specificity | Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non-neuronal tissues. |
Function | RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5: Reduced affinity for RNA. |
Peptide Name | Polypyrimidine Tract-Binding Protein 2 Neural Polypyrimidine Tract-Binding Protein Neurally-Enriched Homolog Of Ptb Ptb-Like Protein |
Cellular Localisation | Nucleus |
Alternative Peptide Names | Polypyrimidine Tract-Binding Protein 2 protein Neural Polypyrimidine Tract-Binding Protein protein Neurally-Enriched Homolog Of Ptb protein Ptb-Like Protein protein PTBP2 protein NPTB protein PTB protein PTBLP protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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