产品详情
简单介绍:
Human CC2D1A (Coiled Coil And C2 Domain Containing Protein 1A) Sandwich ELISA Kit Ready-To-Use (STJE0014111)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.128ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This CC2D1A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | CC2D1A |
Gene ID: | 54862 |
Uniprot ID: | C2D1A_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Phosphorylation on Ser-208 by CDK1 promotes spindle pole localization and association with SCC1/RAD21. |
Function | Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses. Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis. |
Protein Name | Coiled-Coil And C2 Domain-Containing Protein 1a Akt Kinase-Interacting Protein 1 Five Prime Repressor Element Under Dual Repression-Binding Protein 1 Fre Under Dual Repression-Binding Protein 1 Freud-1 Putative Nf-Kappa-B-Activating Protein 023n |
Database Links | |
Cellular Localisation | Cytoplasm Nucleus Cytoskeleton Microtubule Organizing Center Centrosome |
Alternative ELISA Names | Coiled-Coil And C2 Domain-Containing Protein 1a ELISA kit Akt Kinase-Interacting Protein 1 ELISA kit Five Prime Repressor Element Under Dual Repression-Binding Protein 1 ELISA kit Fre Under Dual Repression-Binding Protein 1 ELISA kit Freud-1 ELISA kit Putative Nf-Kappa-B-Activating Protein 023n ELISA kit CC2D1A ELISA kit AKI1 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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