产品详情

  • 产品名称：Human ASC1 (Asc Type Amino Acid Transporter 1) Sandwich ELISA Kit Ready-To-Use (STJE0013707)

  • 产品型号：STJE0013707
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human ASC1 (Asc Type Amino Acid Transporter 1) Sandwich ELISA Kit Ready-To-Use (STJE0013707)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.063ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This ASC1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: SLC7A10
Gene ID: 56301
Uniprot ID: AAA1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle.
Post Translational Modifications
Function Associates with SLC3A2/4F2hc to form a functional heterodimeric complex that translocates small neutral L- and D-amino acids across the plasma membrane. Preferentially mediates exchange transport, but can also operate via facilitated diffusion. Acts as a major transporter for glycine, L- and D-serine in the central nervous system. At the spinal cord and brainstem regulates glycine metabolism and glycinergic inhibitory neurotransmission by providing for glycine de novo synthesis from L-serine and glycine recycling from astrocytes to glycinergic motor neurons. At Schaffer collateral-CA1 synapses mediates D-serine and glycine release that modulates post-synaptic activation of NMDA receptors and excitatory glutamatergic transmission. May regulate D-serine release from mesenchymal progenitors located in developing subcutaneous adipose tissue, favoring white adipocyte over thermogenic beige adipocyte lineage commitment.
Protein Name Asc-Type Amino Acid Transporter 1
Asc-1
Solute Carrier Family 7 Member 10
Database Links Reactome: R-HSA-210991
Reactome: R-HSA-352230
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Colocalizes With Olig2 In Astrocytic Processes
Localizes To The Plasma Membrane In Mature Adipocytes And To Intracellular Structures In Preadipocytes
Alternative ELISA Names Asc-Type Amino Acid Transporter 1 ELISA kit
Asc-1 ELISA kit
Solute Carrier Family 7 Member 10 ELISA kit
SLC7A10 ELISA kit
ASC1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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