产品详情

  • 产品名称：IFI6 Blocking Peptide for STJ505936 peptide (STJ505722)

  • 产品型号：STJ505722-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
IFI6 Blocking Peptide for STJ505936 peptide (STJ505722)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: IFI6 Blocking Peptide for STJ505936 is synthetically produced from the 80-130 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: IFI6
Gene ID: 2537
Uniprot ID: IFI6_HUMAN
Immunogen Region: 80-130
Specificity: This blocking peptide is recommended for use in combination with IFI6 antibody, STJ505936
Immunogen: Synthetic peptide take within amino acid region 80-130 on human Interferon alpha-inducible protein 6.
Function Interferon-stimulated protein that plays an important role in innate immune response against a wide variety of viruses. Inhibits flavivirus replication by preventing the formation of virus-induced endoplasmic reticulum membrane invaginations, which are double-membrane vesicles that flaviviruses use for their replication. Has an antiviral activity towards hepatitis C virus/HCV by inhibiting the EGFR signaling pathway, whose activation is required for entry of the virus into cells. Within the nucleus, restricts hepatitis B virus/HBV promoter activity leading to substantial reduction of viral replication and gene expression. Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis. However, it has also been shown to have a pro-apoptotic activity. Modulates innate immune response mediated by RIGI by preventing its activation.
Peptide Name Interferon Alpha-Inducible Protein 6
Interferon-Induced Protein 6-16
Ifi-6-16
Database Links Reactome: R-HSA-909733
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Mitochondrion Inner Membrane
Alternative Peptide Names Interferon Alpha-Inducible Protein 6 protein
Interferon-Induced Protein 6-16 protein
Ifi-6-16 protein
IFI6 protein
G1P3 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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