产品详情
简单介绍:
Human TSLP protein (Recombinant) (C-His) (STJP001192)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human TSLP-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Gene Symbol: | TSLP |
Gene ID: | 85480 |
Uniprot ID: | TSLP_HUMAN |
Immunogen Region: | Tyr29-Gln159 |
Immunogen: | Recombinant Human TSLP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Tyr29-Gln159) of human TSLP (Accession #NP_149024.1) fused with a 6×His tag at the C-terminus. |
Tissue Specificity | Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva. |
Function | Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. |
Protein Name | Thymic Stromal Lymphopoietin |
Database Links | Reactome: R-HSA-1266695 |
Cellular Localisation | Secreted |
Alternative Protein Names | Thymic Stromal Lymphopoietin protein TSLP protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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