产品详情
简单介绍:
PDE4D Positive Control for STJ502329 peptide (STJ505271)
详情介绍:
Applications: | WB |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | PDE4D Positive Control for STJ502329 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: | WB: 1:500 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | PDE4B |
Gene ID: | 5142 |
Uniprot ID: | PDE4B_HUMAN |
Specificity: | This is positive control is recommended for use in combination with PDE4D antibody STJ502329. |
Tissue Specificity | Expressed in brain, heart, lung and skeletal muscle. Expressed in white blood cells. Isoform PDE4B5: Brain-specific isoform. |
Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
Peptide Name | Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b Dpde4 Pde32 |
Database Links | Reactome: R-HSA-180024 Q07343-3 |
Cellular Localisation | Isoform Pde4b5: Cytoplasm Cell Membrane |
Alternative Peptide Names | Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b protein Dpde4 protein Pde32 protein PDE4B protein DPDE4 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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