产品详情
简单介绍:
Human TIGIT protein (Recombinant) (C-His & Avi) {Biotin} (STJP002034)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human TIGIT-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications. |
Conjugation: | Biotin |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | TIGIT |
Gene ID: | 201633 |
Uniprot ID: | TIGIT_HUMAN |
Immunogen Region: | Met22-Pro141 |
Immunogen: | Biotinylated Recombinant Human TIGIT Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Met22-Pro141) of Human TIGIT fused with a His tag and Avi tag at the C-terminal. |
Function | Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. |
Protein Name | T-Cell Immunoreceptor With Ig And Itim Domains V-Set And Immunoglobulin Domain-Containing Protein 9 V-Set And Transmembrane Domain-Containing Protein 3 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | T-Cell Immunoreceptor With Ig And Itim Domains protein V-Set And Immunoglobulin Domain-Containing Protein 9 protein V-Set And Transmembrane Domain-Containing Protein 3 protein TIGIT protein VSIG9 protein VSTM3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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