产品详情
简单介绍:
Human Thrombopoietin/THPO protein (Recombinant) (C-His) (STJP000949)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Thrombopoietin/THPO-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Immunoreactivity: | Recombinant Human TPO (50 ng/mL) , IL-3 (15 ng/mL) , IL-6 (15 ng/mL) and IL-11 (15 ng/mL) induce hematopoietic stem and progenitor cells to differentiate into megakaryocytes. After 6 days, the induction of CD41/42+ megakaryocytes was successful.2. Me |
Gene Symbol: | THPO |
Gene ID: | 7066 |
Uniprot ID: | TPO_HUMAN |
Immunogen: | Recombinant Human Thrombopoietin/THPO Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser22-Gly353) of human Thrombopoietin/THPO (Accession #NP_000451.1) fused with a 6×His tag at the C-terminus. |
Function | Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
Protein Name | Thrombopoietin C-Mpl Ligand Ml Megakaryocyte Colony-Stimulating Factor Megakaryocyte Growth And Development Factor Mgdf Myeloproliferative Leukemia Virus Oncogene Ligand |
Database Links | Reactome: R-HSA-76009 |
Cellular Localisation | Secreted |
Alternative Protein Names | Thrombopoietin protein C-Mpl Ligand protein Ml protein Megakaryocyte Colony-Stimulating Factor protein Megakaryocyte Growth And Development Factor protein Mgdf protein Myeloproliferative Leukemia Virus Oncogene Ligand protein THPO protein MGDF protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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