产品详情

  • 产品名称：Orexin A Blocking Peptide for STJ502013 peptide (STJ504437)

  • 产品型号：STJ504437-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Orexin A Blocking Peptide for STJ502013 peptide (STJ504437)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Orexin A Blocking Peptide for STJ502013 is synthetically produced from the 1-50 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Hcrt
Gene ID: 15171
Uniprot ID: OREX_MOUSE
Immunogen Region: 1-50
Specificity: This blocking peptide is recommended for use in combination with Orexin A antibody, STJ502013
Immunogen: Synthetic peptide taken within amino acid region 1-50 on ORXN protein.
Tissue Specificity Restricted to neuronal cell bodies of the dorsal and lateral hypothalamus.
Post Translational Modifications Specific enzymatic cleavages at paired basic residues yield the different active peptides.
Function Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A: Binds to orexin receptors HCRTR1/OX1R and HCRTR2/OX2R with a high affinity. Stimulates food intake. Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner. Orexin-B: Binds to orexin receptor HCRTR2/OX2R only. Stimulates food intake. Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner.
Peptide Name Hypocretin Neuropeptide Precursor
Hypocretin
Hcrt
Orexin Precursor
Prepro-Orexin
Preprohypocretin Cleaved Into - Orexin-A
Hypocretin-1
Hcrt1 - Orexin-B
Hypocretin-2
Hcrt2
Database Links Reactome: R-MMU-389397
Reactome: -MMU-416476
Cellular Localisation Rough Endoplasmic Reticulum
Cytoplasmic Vesicle
Synapse
Associated With Perikaryal Rough Endoplasmic Reticulum As Well As Cytoplasmic Large Granular Vesicles At Synapses
Alternative Peptide Names Hypocretin Neuropeptide Precursor protein
Hypocretin protein
Hcrt protein
Orexin Precursor protein
Prepro-Orexin protein
Preprohypocretin Cleaved Into - Orexin-A protein
Hypocretin-1 protein
Hcrt1 - Orexin-B protein
Hypocretin-2 protein
Hcrt2 protein
Hcrt protein
Ox protein
Ppox protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 
网站地图