产品详情

  • 产品名称：Anti-ALAS2 antibody (50-320) (STJ28605)

  • 产品型号：STJ28605
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ALAS2 antibody (50-320) (STJ28605)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ALAS2 (50-320) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ALAS2
Gene ID: 212
Uniprot ID: HEM0_HUMAN
Immunogen Region: 50-320
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human ALAS2 (NP_001033057.1).
Immunogen Sequence: VKTHQFLFGIGRCPILATQG PNCSQIHLKATKAGGDSPSW AKGHCPFMLSELQDGKSKIV QKAAPEVQEDVKAFKTGNYV FSYDQFFRDKIMEKKQDHTY RVFKTVNRWADAYPFAQHFS EASVASKDVSVWCSNDYLGM SRHPQVLQATQETLQRHGAG AGGTRNISGTSKFHVELEQE LAELHQKDSALLFSSCFVAN DSTLFTLAKILPGCEIYSDA GNHASMIQGIRNSGAAKFV
Tissue Specificity Isoform 1: Erythroid-specific. Isoform 2: Erythroid-specific. Isoform 3: Erythroid-specific. Isoform 4: Erythroid-specific.
Function Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products. Contributes significantly to heme formation during erythropoiesis. Isoform 3: Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products. Catalytic activity is 75-85% of isoform 1 activity. Isoform 4: Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products. Catalytic activity is 65-75% of isoform 1 activity.
Protein Name 5-Aminolevulinate Synthase - Erythroid-Specific - Mitochondrial
Alas-E
5-Aminolevulinic Acid Synthase 2
Delta-Ala Synthase 2
Delta-Aminolevulinate Synthase 2
Database Links Reactome: R-HSA-189451
Cellular Localisation Mitochondrion Inner Membrane
Peripheral Membrane Protein
Localizes To The Matrix Side Of The Mitochondrion Inner Membrane
Isoform 4: Mitochondrion Inner Membrane
Alternative Antibody Names Anti-5-Aminolevulinate Synthase - Erythroid-Specific - Mitochondrial antibody
Anti-Alas-E antibody
Anti-5-Aminolevulinic Acid Synthase 2 antibody
Anti-Delta-Ala Synthase 2 antibody
Anti-Delta-Aminolevulinate Synthase 2 antibody
Anti-ALAS2 antibody
Anti-ALASE antibody
Anti-ASB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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