产品详情

  • 产品名称：Anti-ADGRB3 antibody (70-280) (STJ113872)

  • 产品型号：STJ113872
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ADGRB3 antibody (70-280) (STJ113872)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ADGRB3 (70-280) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADGRB3
Gene ID: 577
Uniprot ID: AGRB3_HUMAN
Immunogen Region: 70-280
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 70-280 of human ADGRB3 (NP_001695.1).
Immunogen Sequence: YLKFSKKDLSCSNFSLLAYQ FDHFSHEKIKDLLRKNHSIM QLCNSKNAFVFLQYDKNFIQ IRRVFPTNFPGLQKKGEEDQ KSFFEFLVLNKVSPSQFGCH VLCTWLESCLKSENGRTESC GIMYTKCTCPQHLGEWGIDD QSLILLNNVVLPLNEQTEGC LTQELQTTQVCNLTREAKRP PKEEFGMMGDHTIKSQRPRS VHEKRVPQEQA
Tissue Specificity Strongly expressed in brain. Also detected in heart. Reduced expression in some glioblastoma cell lines.
Post Translational Modifications The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
Function Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity. Promotes myoblast fusion through ELMO/DOCK1.
Protein Name Adhesion G Protein-Coupled Receptor B3
Brain-Specific Angiogenesis Inhibitor 3
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Adhesion G Protein-Coupled Receptor B3 antibody
Anti-Brain-Specific Angiogenesis Inhibitor 3 antibody
Anti-ADGRB3 antibody
Anti-BAI3 antibody
Anti-KIAA0550 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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