产品详情
  • 产品名称:Anti-AGTRAP antibody (93-152) (STJ114071)

  • 产品型号:STJ114071
  • 产品厂商:ST john's laboratory
  • 产品文档:
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简单介绍:
Anti-AGTRAP antibody (93-152) (STJ114071)
详情介绍:
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AGTRAP (93-152) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AGTRAP
Gene ID: 57085
Uniprot ID: ATRAP_HUMAN
Immunogen Region: 93-152
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 93-152 of human AGTRAP (NP_065083.3).
Immunogen Sequence: ILSLLLKPLSCCFVYHMYRE RGGELLVHTGFLGSSQDRSA YQTIDSAEAPADPFAVPEGR
Tissue Specificity Ubiquitous but more abundant in kidney, heart, pancreas and thyroid.
Function Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
Protein Name Type-1 Angiotensin Ii Receptor-Associated Protein
At1 Receptor-Associated Protein
Database Links Reactome: R-HSA-6802952
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Cytoplasmic Vesicle Membrane
Present In Perinuclear Vesicular Membranes
Endoplasmic Reticulum
Golgi And Endocytic Vesicles
Alternative Antibody Names Anti-Type-1 Angiotensin Ii Receptor-Associated Protein antibody
Anti-At1 Receptor-Associated Protein antibody
Anti-AGTRAP antibody
Anti-ATRAP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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