产品详情

  • 产品名称：Anti-AGBL5 antibody (499-549 aa) (STJ194382)

  • 产品型号：STJ194382
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-AGBL5 antibody (499-549 aa) (STJ194382)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cytosolic carboxypeptidase-like protein 5 (499-549 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AGBL5
Gene ID: 60509
Uniprot ID: CBPC5_HUMAN
Immunogen Region: 499-549 aa
Specificity: This antibody detects endogenous levels of CBPC5 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human CBPC5 at the amino acid range 499-549
Function Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Cleaves alpha- and gamma-linked polyglutamate tubulin side-chain, as well as the branching point glutamate. Also catalyzes the removal of alpha-linked glutamate residues from the carboxy-terminus of alpha-tubulin. Mediates deglutamylation of nucleotidyltransferase CGAS, leading to CGAS antiviral defense response activation.
Protein Name Cytosolic Carboxypeptidase-Like Protein 5
Atp/Gtp-Binding Protein-Like 5
Protein Deglutamylase Ccp5
Database Links Reactome: R-HSA-8955332
Cellular Localisation Cytoplasm
Cytosol
Nucleus
Cytoskeleton
Spindle
Midbody
Mainly Cytoplasmic
Slight Accumulation In The Nucleus Is Observed
Colocalizes With Alpha-Tubulin In The Mitotic Spindle And With Midbody Microtubules In The Intercellular Bridges Formed During Cytokinesis
Alternative Antibody Names Anti-Cytosolic Carboxypeptidase-Like Protein 5 antibody
Anti-Atp/Gtp-Binding Protein-Like 5 antibody
Anti-Protein Deglutamylase Ccp5 antibody
Anti-AGBL5 antibody
Anti-CCP5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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