产品详情

  • 产品名称：Human ACACa (Acetyl Coenzyme A Carboxylase Alpha) Sandwich ELISA Kit Ready-To-Use (STJE0013208)

  • 产品型号：STJE0013208
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human ACACa (Acetyl Coenzyme A Carboxylase Alpha) Sandwich ELISA Kit Ready-To-Use (STJE0013208)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 1.09ng/mL
Detection Limit: 3.12-200ng/mL
Short Description: This ACACa Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: ACACA
Gene ID: 31
Uniprot ID: ACACA_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity Expressed in brain, placenta, skeletal muscle, renal, pancreatic and adipose tissues.expressed at low level in pulmonary tissue.not detected in the liver.
Post Translational Modifications Phosphorylation on Ser-1263 is required for interaction with BRCA1. Phosphorylation at Ser-80 by AMPK inactivates enzyme activity. The biotin cofactor is covalently attached to the central biotinyl-binding domain and is required for the catalytic activity.
Function Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosesynthesis. This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA.
Protein Name Acetyl-Coa Carboxylase 1
Acc1
Acetyl-Coenzyme A Carboxylase Alpha
Acc-Alpha
Database Links Reactome: R-HSA-163765
Reactome: R-HSA-196780
Reactome: R-HSA-200425
Reactome: R-HSA-2426168
Reactome: R-HSA-3371599
Reactome: R-HSA-75105
Cellular Localisation Cytoplasm
Cytosol
Alternative ELISA Names Acetyl-Coa Carboxylase 1 ELISA kit
Acc1 ELISA kit
Acetyl-Coenzyme A Carboxylase Alpha ELISA kit
Acc-Alpha ELISA kit
ACACA ELISA kit
ACAC ELISA kit
ACC1 ELISA kit
ACCA ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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