产品详情
简单介绍:
Anti-ADRM1 antibody (STJA0007048)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Proteasomal ubiquitin receptor ADRM1 is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ADRM1 |
Gene ID: | 11047 |
Uniprot ID: | ADRM1_HUMAN |
Specificity: | This antibody detects endogenous levels of ADRM1 at Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from human ADRM1 |
Function | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex. |
Protein Name | Proteasomal Ubiquitin Receptor Adrm1 110 Kda Cell Membrane Glycoprotein Gp110 Adhesion-Regulating Molecule 1 Arm-1 Proteasome Regulatory Particle Non-Atpase 13 Hrpn13 Rpn13 Homolog |
Database Links | Reactome: R-HSA-5689603 Reactome: R-HSA-5689880 |
Cellular Localisation | Cytoplasm Nucleus |
Alternative Antibody Names | Anti-Proteasomal Ubiquitin Receptor Adrm1 antibody Anti-110 Kda Cell Membrane Glycoprotein antibody Anti-Gp110 antibody Anti-Adhesion-Regulating Molecule 1 antibody Anti-Arm-1 antibody Anti-Proteasome Regulatory Particle Non-Atpase 13 antibody Anti-Hrpn13 antibody Anti-Rpn13 Homolog antibody Anti-ADRM1 antibody Anti-GP110 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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