产品详情

  • 产品名称：Anti-ACOT8 antibody (131-180 aa) (STJ91454)

  • 产品型号：STJ91454
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ACOT8 antibody (131-180 aa) (STJ91454)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Acyl-coenzyme A thioesterase 8 (131-180 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACOT8
Gene ID: 10005
Uniprot ID: ACOT8_HUMAN
Immunogen Region: 131-180 aa
Specificity: ACOT8 Polyclonal Antibody detects endogenous levels of ACOT8 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ACOT8 at the amino acid range 131-180
Function Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays no strong substrate specificity with respect to the carboxylic acid moiety of Acyl-CoAs. Hydrolyzes medium length (C2 to C20) straight-chain, saturated and unsaturated acyl-CoAS but is inactive towards substrates with longer aliphatic chains. Moreover, it catalyzes the hydrolysis of CoA esters of bile acids, such as choloyl-CoA and chenodeoxycholoyl-CoA and competes with bile acid CoA:amino acid N-acyltransferase (BAAT). Is also able to hydrolyze CoA esters of dicarboxylic acids. It is involved in the metabolic regulation of peroxisome proliferation. (Microbial infection) May mediate Nef-induced down-regulation of CD4 cell-surface expression.
Protein Name Acyl-Coenzyme A Thioesterase 8
Acyl-Coa Thioesterase 8
Choloyl-Coenzyme A Thioesterase
Hiv-Nef-Associated Acyl-Coa Thioesterase
Peroxisomal Acyl-Coa Thioesterase 2
Pte-2
Peroxisomal Acyl-Coenzyme A Thioester Hydrolase 1
Pte-1
Peroxisomal Long-Chain Acyl-Coa Thioesterase 1
Thioesterase Ii
Hacte-Iii
Hacteiii
Hte
Database Links Reactome: R-HSA-193368
Reactome: R-HSA-2046106
Reactome: R-HSA-389887
Reactome: R-HSA-390247
Reactome: R-HSA-9033241
Cellular Localisation Peroxisome Matrix
Predominantly Localized In The Peroxisome But A Localization To The Cytosol Cannot Be Excluded
Alternative Antibody Names Anti-Acyl-Coenzyme A Thioesterase 8 antibody
Anti-Acyl-Coa Thioesterase 8 antibody
Anti-Choloyl-Coenzyme A Thioesterase antibody
Anti-Hiv-Nef-Associated Acyl-Coa Thioesterase antibody
Anti-Peroxisomal Acyl-Coa Thioesterase 2 antibody
Anti-Pte-2 antibody
Anti-Peroxisomal Acyl-Coenzyme A Thioester Hydrolase 1 antibody
Anti-Pte-1 antibody
Anti-Peroxisomal Long-Chain Acyl-Coa Thioesterase 1 antibody
Anti-Thioesterase Ii antibody
Anti-Hacte-Iii antibody
Anti-Hacteiii antibody
Anti-Hte antibody
Anti-ACOT8 antibody
Anti-ACTEIII antibody
Anti-PTE1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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