产品详情

  • 产品名称：Deformed Epidermal Autoregulatory Factor 1 Blocking Peptide for STJ500748 peptide (STJ505547)

  • 产品型号：STJ505547-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Deformed Epidermal Autoregulatory Factor 1 Blocking Peptide for STJ500748 peptide (STJ505547)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Deformed Epidermal Autoregulatory Factor 1 Blocking Peptide for STJ500748 is synthetically produced from the 500-565 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Deaf1
Gene ID: 54006
Uniprot ID: DEAF1_MOUSE
Immunogen Region: 500-565
Specificity: This blocking peptide is recommended for use in combination with Deformed Epidermal Autoregulatory Factor 1 antibody, STJ500748
Immunogen: Synthetic peptide taken within amino acid region 500-565 on mouse Deformed epidermal autoregulatory factor 1 homolog protein.
Tissue Specificity Ubiquitously expressed during embryogenesis, with higher expression in regions of the central nervous system, dorsal root ganglia, submandibular gland, epidermis and breast. In 12-week-old NOD mice, expression of isoform 2 is sevenfold higher in lymph node stromal elements than in T-cells and tenfold higher than in B-cells.
Post Translational Modifications May be phosphorylated by DNA-PK complex in a DNA independent manner (in vitro).
Function Transcription factor that binds to sequence with multiple copies of 5'-TTCCGG-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. Regulates epithelial cell proliferation and side-branching in the mammary gland. Required for neural tube closure and skeletal patterning. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 2. Isoform 2 may inhibit transcriptional activity of isoform 1 by interacting with it and retaining it in the cytoplasm. Transcriptional activator of EIF4G3. May also involved in behavior.
Peptide Name Deformed Epidermal Autoregulatory Factor 1 Homolog
Nuclear Deaf-1-Related Transcriptional Regulator
Nudr
Cellular Localisation Isoform 1: Nucleus
Cytoplasm
Isoform 2: Cytoplasm
Nucleus
Displays Some Nuclear Localization When Expressed With Isoform 1
Suggesting That It May Heterodimerize With Isoform 1 And Shuttle To The Nucleus Using The Nuclear Localization Signal Of Isoform 1
Alternative Peptide Names Deformed Epidermal Autoregulatory Factor 1 Homolog protein
Nuclear Deaf-1-Related Transcriptional Regulator protein
Nudr protein
Deaf1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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