产品详情
简单介绍:
Human CDH6/K-Cadherin protein (Recombinant) (C-His) (STJP001013)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human CDH6/K-Cadherin-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human CDH6 at 1 Mu g/mL (100 Mu L/well) can bind CDH6 Mouse mAb with a linear range of 0.05-6.31 ng/mL. |
Gene Symbol: | CDH6 |
Gene ID: | 1004 |
Uniprot ID: | CADH6_HUMAN |
Immunogen: | Recombinant Human CDH6/K-Cadherin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Thr 19-Ala 615 ) of human K-Cadherin (Accession #NP_004923.1) fused with a 6×His tag at the C-terminus. |
Tissue Specificity | Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. |
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. |
Protein Name | Cadherin-6 Kidney Cadherin K-Cadherin |
Database Links | Reactome: R-HSA-418990 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | Cadherin-6 protein Kidney Cadherin protein K-Cadherin protein CDH6 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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